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KMID : 0368820110500050368
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Journal of the Korean Neuropsychiatr Association
2011 Volume.50 No. 5 p.368 ~ p.374
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Comparison of the Subjective Quality of Life in Four Groups of Antipsychotics by Risk of Weight Gain in Patients with Schizophrenia
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Kim Kyoung-Hoon
Kang Shi-Hyun
Kang Gwon-Young
Lee Ka-Hee
Kim Kwon-Kon
Soh Min-Ah
Ahn Kil-Joon
Lee Jong-Il
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Abstract
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Objectives: The aim of this cross-sectional study was to compare the subjective quality of life in the four groups of antipsychotics according to the risk of weight gain in patients with schizophrenia.
Methods: One hundred and thirty-two patients with schizophrenia that had taken the same antipsychotics for more than 1 year were enrolled in the analyses. Anti-psychotic agents were classified by the risk of weight gain into four groups : serious, common, not unusual, and unusual. The quality of life was measured with the Schizophrenia Quality of Life Scale Korean version, 4th Revision (SQLS-R4K). We analyzed the correlation between the total score of SQLS-R4K and clinical variables.
Results: The SQLS-R4K score was significantly different in the four anti-psychotic groups (F=5.200, p=0.002). Gender, type of anti-psychotics (typical, atypical), duration of treatment with current antipsychotics, duration of illness, and Body Mass Index were not significantly correlated with the SQLS-R4K score.
Conclusion: The subjective quality of life was different according to the risk of weight gain groups of anti-psychotic agents.
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KEYWORD
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Schizophrenia, Quality of life, Antipsychotics, Weight gain risk
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